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KMID : 1103720180780060408
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Journal of the Korean Society of Radiology
2018 Volume.78 No. 6 p.408 ~ p.411
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Early Evaluation of Inflammatory Focus and Treatment Response Using 18F-Sodium Fluoride Bone Positron Emission Tomography/Computed Tomography in Patients with Metallic Implants: A Case Report
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Moon Ji-Hae
Lee Sang-Mi
Hong Chang-Hwa
Lee Jeong-Won
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Abstract
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We report a case of a 76-year-old woman with elevated serum C-reactive protein levels for two weeks after spinal surgery. 99mTc-labeled white blood cell scan and dual 18F-sodium-fluoride (18F-NaF) bone positron emission tomography/computed tomography (PET/CT) were used to detect the site of inflammation. Using non-attenuation corrected images, soft tissue inflammation was detected without metal artifact. Antibiotic treatment attenuated inflammation as seen in an early-phase scan using follow-up 18F-NaF bone PET/CT. This case demonstrates the role of 18F-NaF bone PET/CT in the detection of inflammation sites, and can be used to evaluate treatment response in patients with metallic implants.
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KEYWORD
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Sodium Fluoride, Positron Emission Tomography Computed Tomography, Inflammation, Treatment Outcome
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